Restriction of Porcine Endogenous Retrovirus by Porcine APOBEC3 Cytidine Deaminases

Xenotransplantation of porcine cells, tissues, and organs shows promise to surmount the shortage of human donor materials. Among the barriers to pig-to-human xenotransplantation are porcine endogenous retroviruses (PERV) since functional representatives of the two polytropic classes, PERV-A and PERV...

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Detalhes bibliográficos
Main Authors: Dörrschuck, Eva, Fischer, Nicole, Bravo, Ignacio G., Hanschmann, Kay-Martin, Kuiper, Heidi, Spötter, Andreas, Möller, Ronny, Cichutek, Klaus, Münk, Carsten, Tönjes, Ralf R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126140/
https://ncbi.nlm.nih.gov/pubmed/21307203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01880-10
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