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The IRF-3/Bax-Mediated Apoptotic Pathway, Activated by Viral Cytoplasmic RNA and DNA, Inhibits Virus Replication

Induction of apoptosis in cells infected by Sendai virus (SeV), which triggers the cytosolic RIG-I pathway, requires the presence of interferon regulatory factor 3 (IRF-3). Independent of IRF-3's transcriptional role, a novel IRF-3 activation pathway causes its interaction with the proapoptotic...

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書誌詳細
主要な著者: Chattopadhyay, Saurabh, Yamashita, Michifumi, Zhang, Ying, Sen, Ganes C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126131/
https://ncbi.nlm.nih.gov/pubmed/21307205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02133-10
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