Vif Substitution Enables Persistent Infection of Pig-Tailed Macaques by Human Immunodeficiency Virus Type 1

Among Old World monkeys, pig-tailed macaques (Pt) are uniquely susceptible to human immunodeficiency virus type 1 (HIV-1), although the infection does not persist. We demonstrate that the susceptibility of Pt T cells to HIV-1 infection is due to the absence of postentry inhibition by a TRIM5 isoform...

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Bibliografiska uppgifter
Huvudupphovsmän: Thippeshappa, Rajesh, Polacino, Patricia, Yu Kimata, Monica T., Siwak, Edward B., Anderson, David, Wang, Weiming, Sherwood, Laura, Arora, Reetakshi, Wen, Michael, Zhou, Paul, Hu, Shiu-Lok, Kimata, Jason T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2011
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126129/
https://ncbi.nlm.nih.gov/pubmed/21289128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02438-10
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