Oligonucleotide Motifs That Disappear during the Evolution of Influenza Virus in Humans Increase Alpha Interferon Secretion by Plasmacytoid Dendritic Cells

CpG motifs in an A/U context have been preferentially eliminated from classical H1N1 influenza virus genomes during virus evolution in humans. The hypothesis of the current work is that CpG motifs in a uracil context represent sequence patterns with the capacity to induce an immune response, and the...

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Bibliografiske detaljer
Main Authors: Jimenez-Baranda, Sonia, Greenbaum, Benjamin, Manches, Olivier, Handler, Jesse, Rabadán, Raúl, Levine, Arnold, Bhardwaj, Nina
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126114/
https://ncbi.nlm.nih.gov/pubmed/21307198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01908-10
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