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Targeted therapy for metastatic renal cell carcinoma: current treatment and future directions

An understanding of vascular endothelial growth factor (VEGF) and mammalian target of rapamycin (mTOR) pathways has greatly changed the way metastatic renal cell carcinoma (RCC) is treated. Based on available phase III randomized trials, anti-VEGF agents such as sunitinib, sorafenib, bevacizumab-bas...

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Autors principals: Heng, Daniel Y.C., Kollmannsberger, Christian, Chi, Kim N.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126007/
https://ncbi.nlm.nih.gov/pubmed/21789125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834009352498
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