Soluble VEGF isoforms are essential for establishingepiphyseal vascularization and regulating chondrocyte development and survival

VEGF is crucial for metaphyseal bone vascularization. In contrast, the angiogenic factors required for vascularization of epiphyseal cartilage are unknown, although this represents a developmentally and clinically important aspect of bone growth. The VEGF gene is alternatively transcribed into VEGF(...

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Autori principali: Maes, Christa, Stockmans, Ingrid, Moermans, Karen, Van Looveren, Riet, Smets, Nico, Carmeliet, Peter, Bouillon, Roger, Carmeliet, Geert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC312596/
https://ncbi.nlm.nih.gov/pubmed/14722611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419383
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