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Structure and Mutational Analysis of the Archaeal GTP:AdoCbi-P Guanylyltransferase (CobY) from Methanocaldococcus jannaschii: Insights into GTP Binding and Dimerization

In archaea and bacteria, the late steps in adenosylcobalamin (AdoCbl) biosynthesis are collectively known as the nucleotide loop assembly (NLA) pathway. In the archaeal and bacterial NLA pathways, two different guanylyltransferases catalyze the activation of the corrinoid. Structural and functional...

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Detalhes bibliográficos
Main Authors: Newmister, Sean A., Otte, Michele M., Escalante-Semerena, Jorge C., Rayment, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125946/
https://ncbi.nlm.nih.gov/pubmed/21542645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200329t
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