Lcl of Legionella pneumophila Is an Immunogenic GAG Binding Adhesin That Promotes Interactions with Lung Epithelial Cells and Plays a Crucial Role in Biofilm Formation

Legionellosis is mostly caused by Legionella pneumophila and is defined by a severe respiratory illness with a case fatality rate ranging from 5 to 80%. In vitro and in vivo, interactions of L. pneumophila with lung epithelial cells are mediated by the sulfated glycosaminoglycans (GAGs) of the host...

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Détails bibliographiques
Auteurs principaux: Duncan, Carla, Prashar, Akriti, So, Jannice, Tang, Patrick, Low, Donald E., Terebiznik, Mauricio, Guyard, Cyril
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125840/
https://ncbi.nlm.nih.gov/pubmed/21422183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01304-10
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