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Large-Scale Assessment of the Zebrafish Embryo as a Possible Predictive Model in Toxicity Testing

BACKGROUND: In the drug discovery pipeline, safety pharmacology is a major issue. The zebrafish has been proposed as a model that can bridge the gap in this field between cell assays (which are cost-effective, but low in data content) and rodent assays (which are high in data content, but less cost-...

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Detalles Bibliográficos
Main Authors: Ali, Shaukat, van Mil, Harald G. J., Richardson, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125172/
https://ncbi.nlm.nih.gov/pubmed/21738604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021076
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