Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output

The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. Nucleosome number in cells was considered fixed, but recently aging yeast and mammalian cells were shown to contain fewer nucleosomes. We s...

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Bibliografische gegevens
Hoofdauteurs: Celona, Barbara, Weiner, Assaf, Di Felice, Francesca, Mancuso, Francesco M., Cesarini, Elisa, Rossi, Riccardo L., Gregory, Lorna, Baban, Dilair, Rossetti, Grazisa, Grianti, Paolo, Pagani, Massimiliano, Bonaldi, Tiziana, Ragoussis, Jiannis, Friedman, Nir, Camilloni, Giorgio, Bianchi, Marco E., Agresti, Alessandra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125158/
https://ncbi.nlm.nih.gov/pubmed/21738444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001086
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