Residual Embryonic Cells as Precursors of a Barrett's-Like Metaplasia

Barrett's esophagus is an intestine-like metaplasia and precursor of esophageal adenocarcinoma. Triggered by gastroesophageal reflux disease, the origin of this metaplasia remains unknown. p63-deficient mice, which lack squamous epithelia, may model acid-reflux damage. We show here that p63 nul...

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Main Authors: Wang, Xia, Ouyang, Hong, Yamamoto, Yusuke, Kumar, Pooja Ashok, Wei, Tay Seok, Dagner, Rania, Vincent, Matthew, Lu, Xin, Bellizzi, Andrew M., Yu, Ho Khek, Crum, Christopher P., Xian, Wa, McKeon, Frank
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125107/
https://ncbi.nlm.nih.gov/pubmed/21703447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.05.026
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