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IgA in the horse: cloning of equine polymeric Ig receptor and J chain and characterization of recombinant forms of equine IgA

As in other mammals, immunoglobulin A (IgA) in the horse has a key role in immune defense. To better dissect equine IgA function, we isolated complementary DNA (cDNA) clones for equine J chain and polymeric Ig receptor (pIgR). When coexpressed with equine IgA, equine J chain promoted efficient IgA p...

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Bibliographic Details
Main Authors: Lewis, M J, Wagner, B, Irvine, R M, Woof, J M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125105/
https://ncbi.nlm.nih.gov/pubmed/20631692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.38
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