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Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-κB pathways in intestinal epithelial cells

The polymeric immunoglobulin receptor (pIgR) transports IgA antibodies across intestinal epithelial cells (IECs). Expression of pIgR is upregulated by proinflammatory signaling pathways via activation of nuclear factor-κB (NF-κB). Here, we examined the contributions of the RelA-dependent classical a...

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Detalhes bibliográficos
Main Authors: Bruno, M E C, Frantz, A L, Rogier, E W, Johansen, F-E, Kaetzel, C S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125104/
https://ncbi.nlm.nih.gov/pubmed/21451502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.8
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