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Role of glutathione-s-transferase and CYP1A1*2A polymorphisms in the therapy outcome of south Indian acute lymphoblastic leukemia patients

BACKGROUND: Polymorphisms in the drug-metabolizing enzymes are found to be associated with the inter-individual variation in response to a particular drug. Glutathione S-transferases (GSTs) are involved in the metabolism of several anticancer drugs, including alkylating agents, anthracyclines, and c...

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Detalhes bibliográficos
Main Authors: Suneetha, K. J., Nancy, K. Nirmala, Rajalekshmy, K. R., Rama, R., Sagar, T. G., Rajkumar, T.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124985/
https://ncbi.nlm.nih.gov/pubmed/21731212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5851.81886
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