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Preserving fertility during cancer treatment

Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179– 1185). The findings could lead to new ways to protect germ cells from the...

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Bibliographic Details
Main Author: Woodruff, Teresa K
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124896/
https://ncbi.nlm.nih.gov/pubmed/19812566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1009-1124
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