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The AT-rich tract of the SV40 ori core: negative synergism and specific recognition by single stranded and duplex DNA binding proteins.

The SV40 origin of replication comprises a run of thymine and adenine residues. Integrity of this AT-rich sequence is known to be essential for replication. We set out to study whether or not these elements can work synergistically to sustain replication. Quite surprisingly, additional copies of the...

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Main Authors: Galli, I, Iguchi-Ariga, S M, Ariga, H
格式: Artigo
語言:Inglês
出版: 1992
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC312485/
https://ncbi.nlm.nih.gov/pubmed/1321411
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