Papillomavirus-Specific CD4+ T-cells Exhibit Reduced STAT-5 signaling and Altered Cytokine Profiles in Patients with Recurrent Respiratory Papillomatosis

Recurrent Respiratory Papillomatosis (RRP) is caused by HPV-6 or -11. Specific HLA-DR haplotypes, DRB1*01:02 and DRB1*03:01 are associated with the development of RRP, disease severity, and T(H)2-like responses to HPV early proteins. T(H)1-like responses to HPV proteins have been shown to be protect...

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Main Authors: James, Eddie A., DeVoti, James A., Rosenthal, David W., Hatam, Lynda J., Steinberg, Bettie M., Abramson, Allan L., Kwok, William W., Bonagura, Vincent R.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124771/
https://ncbi.nlm.nih.gov/pubmed/21531896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004181
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