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Systems pharmacology assessment of the 5-fluorouracil pathway
AIM: To assess the impact of the 5-fluorouracil (5-FU) drug-pathway genes on cytotoxicity, and determine whether loss-of-function analyses coupled with functional assays can help prioritize pharmacogenomic candidate genes. MATERIALS & METHODS: Dose-response experiments were used to quantify the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124653/ https://ncbi.nlm.nih.gov/pubmed/21449674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.10.188 |
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