Normalization in MALDI-TOF imaging datasets of proteins: practical considerations

Normalization is critically important for the proper interpretation of matrix-assisted laser desorption/ionization (MALDI) imaging datasets. The effects of the commonly used normalization techniques based on total ion count (TIC) or vector norm normalization are significant, and they are frequently...

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Autores principales: Deininger, Sören-Oliver, Cornett, Dale S., Paape, Rainer, Becker, Michael, Pineau, Charles, Rauser, Sandra, Walch, Axel, Wolski, Eryk
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2011
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124646/
https://ncbi.nlm.nih.gov/pubmed/21479971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-4929-z
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