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Analysis of Catalytic Determinants of Diaminopimelate and Ornithine Decarboxylases Using Alternate Substrates

Diaminopimelate decarboxylase (DAPDC) and ornithine decarboxylase (ODC) are pyridoxal 5′-phosphate dependent enzymes that are critical to microbial growth and pathogenicity. The latter is the target of drugs that cure African sleeping sickness, while the former is an attractive target for antibacter...

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Bibliografski detalji
Glavni autori: Fogle, Emily J., Toney, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124589/
https://ncbi.nlm.nih.gov/pubmed/21640851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2011.05.014
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