ENHANCED REPLICATION AND PATHOGENESIS OF MOLONEY MURINE LEUKEMIA VIRUS IN MICE DEFECTIVE IN THE MURINE APOBEC3 GENE

Human APOBEC3G (hA3G), a member of the AID/APOBEC family of deaminases, is a restriction factor for human immunodeficiency virus (HIV). In the absence of the viral Vif protein hA3G is packaged into virions and during reverse transcription in a recipient cell it deaminates cytosines, leading to G --&...

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Detalhes bibliográficos
Main Authors: Low, Audrey, Okeoma, Chioma M., Lovsin, Nika, de las Heras, Marcelo, Taylor, Thomas H., Peterlin, B. Matija, Ross, Susan R., Fan, Hung
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124558/
https://ncbi.nlm.nih.gov/pubmed/19150103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.11.051
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