Multiple Oxygen Tension Environments Reveal Diverse Patterns of Transcriptional Regulation in Primary Astrocytes

The central nervous system normally functions at O(2) levels which would be regarded as hypoxic by most other tissues. However, most in vitro studies of neurons and astrocytes are conducted under hyperoxic conditions without consideration of O(2)-dependent cellular adaptation. We analyzed the reacti...

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Detalhes bibliográficos
Main Authors: Chadwick, Wayne, Boyle, John P., Zhou, Yu, Wang, Liyun, Park, Sung-Soo, Martin, Bronwen, Wang, Rui, Becker, Kevin G., Wood, William H., Zhang, Yongqing, Peers, Chris, Maudsley, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124552/
https://ncbi.nlm.nih.gov/pubmed/21738745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021638
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