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Grape Seed Proanthocyanidins Inhibit Melanoma Cell Invasiveness by Reduction of PGE(2) Synthesis and Reversal of Epithelial-to-Mesenchymal Transition

Melanoma is the leading cause of death from skin disease due, in large part, to its propensity to metastasize. We have examined the effect of grape seed proanthocyanidins (GSPs) on melanoma cancer cell migration and the molecular mechanisms underlying these effects using highly metastasis-specific h...

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Détails bibliographiques
Auteurs principaux: Vaid, Mudit, Singh, Tripti, Katiyar, Santosh K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124524/
https://ncbi.nlm.nih.gov/pubmed/21738696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021539
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