Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells

Polarized molecular activities play important roles in guiding the cell toward persistent and directional migration. In this study, the polarized distributions of the activities of phosphatidylinositol 3-kinase (PI3K) and the Rac1 small GTPase were monitored using chimeric fluorescent proteins (FPs)...

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Bibliografiske detaljer
Main Authors: Lu, Shaoying, Kim, Tae-jin, Chen, Chih-En, Ouyang, Mingxing, Seong, Jihye, Liao, Xiaoling, Wang, Yingxiao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124492/
https://ncbi.nlm.nih.gov/pubmed/21738630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021293
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