The liver-specific promoter of the human insulin-like growth factor II gene is activated by CCAAT/enhancer binding protein (C/EBP).

The human gene coding for insulin-like growth factor II (IGF-II) contains four promoters (P1-P4), that are subjected to tissue-specific and development-dependent regulation. Expression of promoter P1 is detected only in adult liver tissue, whereas promoter P3 is the major IGF-II promoter in fetal li...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	van Dijk, M A, Rodenburg, R J, Holthuizen, P, Sussenbach, J S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1992
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.12.3099
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