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Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice

Amphotericin B deoxycholate (AmB), a classic antifungal drug, remains the initial treatment of choice for deep fungal infections, but it is not appropriate for treatment of cryptococcal meningitis due to its inability to pass through the blood–brain barrier (BBB). We examined the efficacy of amphote...

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Detalhes bibliográficos
Main Authors: Xu, Nan, Gu, Julin, Zhu, Yuanjie, Wen, Hai, Ren, Qiushi, Chen, Jianghan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124396/
https://ncbi.nlm.nih.gov/pubmed/21720503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S17503
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