A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets

Scopolamine hydrobromide (SH)-loaded microparticles were prepared from a colloidal fluid containing ionotropic-gelated chitosan nanoparticles using a spray-drying method. The spray-dried microparticles were then formulated into orally disintegrating tablets (ODTs) using a wet granulation tablet form...

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Bibliographic Details
Main Authors: Li, Feng-Qian, Yan, Cheng, Bi, Juan, Lv, Wei-Lin, Ji, Rui-Rui, Chen, Xu, Su, Jia-Can, Hu, Jin-Hong
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2011
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124395/
https://ncbi.nlm.nih.gov/pubmed/21720502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S17900
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