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Synthesis and Neurotoxicity Profile of 2,4,5-Trihydroxymethamphetamine and its 6-(N-Acetylcystein-S-yl) Conjugate

The purpose of the present study was to determine if trihydroxymethamphetamine (THMA), a metabolite of methylenedioxymethamphetamine (MDMA, “ecstasy”) or its thioether conjugate, 6-(N-acetylcystein-S-yl)-2,4,5-trihydroxymethamphetamine (6-NAC-THMA), plays a role in the lasting effects of MDMA on bra...

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Autors principals: Neudörffer, Anne, Mueller, Melanie, Martinez, Claire-Marie, Mechan, Annis, McCann, Una, Ricaurte, George A., Largeron, Martine
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124246/
https://ncbi.nlm.nih.gov/pubmed/21557581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2001459
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