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Multiple alignment using simulated annealing: branch point definition in human mRNA splicing.

A method for the simultaneous alignment of a very large number of sequences using simulated annealing is presented. The total running time of the algorithm does not depend explicitly on the number of sequences treated. The method has been used for the simultaneous alignment of 1462 human intron sequ...

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Detalhes bibliográficos
Main Authors: Lukashin, A V, Engelbrecht, J, Brunak, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312386/
https://ncbi.nlm.nih.gov/pubmed/1598209
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