Expression and Regulation of the ΔN and TAp63 Isoforms in Salivary Gland Tumorigenesis: Clinical and Experimental Findings

The TP63 gene, a TP53 homologue, encodes for two main isoforms by different promoters: one retains (TA) and the other lacks (ΔN) the transactivation domain. p63 plays a critical role in the maintenance of basal and myoepithelial cells in ectodermally derived tissues and is implicated in tumorigenesi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mitani, Yoshitsugu, Li, Jie, Weber, Randal S., Lippman, Scott L., Flores, Elsa R., Caulin, Carlos, El-Naggar, Adel K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2011
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123859/
https://ncbi.nlm.nih.gov/pubmed/21703418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.037
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