Targeting ST2L Potentiates CpG-Mediated Therapeutic Effects in a Chronic Fungal Asthma Model

IL-33 and its soluble receptor and cell-associated receptor (ST2L) are all increased in clinical and experimental asthma. The present study addressed the hypothesis that ST2L impairs the therapeutic effects of CpG in a fungal model of asthma. C57BL/6 mice were sensitized to Aspergillus fumigatus and...

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Detalhes bibliográficos
Main Authors: Ramaprakash, Hemanth, Shibata, Takehiko, Duffy, Karen E., Ismailoglu, Ugur B., Bredernitz, Rachel M., Moreira, Ana Paula, Coelho, Ana L., Das, Anuk M., Fursov, Natalie, Chupp, Geoffrey L., Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123853/
https://ncbi.nlm.nih.gov/pubmed/21640974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.032
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