Discoidin Domain Receptor 1 Is a Major Mediator of Inflammation and Fibrosis in Obstructive Nephropathy

The interactions between tubulointerstitial infiltrating cells and the extracellular matrix play an important role in regulating renal fibrosis. Discoidin domain receptor 1 (DDR1) is a nonintegrin tyrosine kinase receptor for collagen implicated in cell adhesion, proliferation, and extracellular mat...

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Autori principali: Guerrot, Dominique, Kerroch, Monique, Placier, Sandrine, Vandermeersch, Sophie, Trivin, Claire, Mael-Ainin, Mouna, Chatziantoniou, Christos, Dussaule, Jean-Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123843/
https://ncbi.nlm.nih.gov/pubmed/21640971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.023
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