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Abnormal Cell Properties and Down-Regulated FAK-Src Complex Signaling in B Lymphoblasts of Autistic Subjects

Recent studies suggest that one of the major pathways to the pathogenesis of autism is reduced cell migration. Focal adhesion kinase (FAK) has an important role in neural migration, dendritic morphological characteristics, axonal branching, and synapse formation. The FAK-Src complex, activated by up...

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Detalhes bibliográficos
Main Authors: Wei, Hongen, Malik, Mazhar, Sheikh, Ashfaq M., Merz, George, Ted Brown, W., Li, Xiaohong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123809/
https://ncbi.nlm.nih.gov/pubmed/21703394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.034
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