A Methyl-Deviator Epigenotype of Estrogen Receptor–Positive Breast Carcinoma Is Associated with Malignant Biology

We broadly profiled DNA methylation in breast cancers (n = 351) and benign parenchyma (n = 47) for correspondence with disease phenotype, using FFPE diagnostic surgical pathology specimens. Exploratory analysis revealed a distinctive primary invasive carcinoma subclass featuring extreme global methy...

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Detalhes bibliográficos
Main Authors: Killian, J.. Keith, Bilke, Sven, Davis, Sean, Walker, Robert L., Jaeger, Erich, Killian, M. Scott, Waterfall, Joshua J., Bibikova, Marina, Fan, Jian-Bing, Smith, William I., Meltzer, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123808/
https://ncbi.nlm.nih.gov/pubmed/21641572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.022
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