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Restriction Enzyme–Mediated Enhanced Detection of Circulating Cell-Free Fetal DNA in Maternal Plasma

A universal method confirming the presence of circulating cell-free fetal (ccff) DNA in maternal plasma is important in the field of noninvasive prenatal diagnostics. Restriction endonuclease digestion of one allele of a single-nucleotide polymorphism (SNP) was used to allow detection of paternal al...

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Detalhes bibliográficos
Main Authors: Tynan, John A., Mahboubi, Payam, Cagasan, Lesley L., van den Boom, Dirk, Ehrich, Mathias, Oeth, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123783/
https://ncbi.nlm.nih.gov/pubmed/21704271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.02.001
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