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Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats

Itch is thought to be signaled by pruritogen-responsive neurons in the superficial spinal dorsal horn. Many neurons here express the substance P NK-1 receptor. We investigated whether neurotoxic destruction of spinal NK-1-expressing neurons affected itch-related scratching behavior. Rats received in...

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Main Authors: Carstens, Earl E., Carstens, Mirela Iodi, Simons, Christopher T., Jinks, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123731/
https://ncbi.nlm.nih.gov/pubmed/20125052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328337310a
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