Systemic BCG Immunization Induces Persistent Lung Mucosal Multifunctional CD4 T(EM) Cells which Expand Following Virulent Mycobacterial Challenge

To more closely understand the mechanisms of how BCG vaccination confers immunity would help to rationally design improved tuberculosis vaccines that are urgently required. Given the established central role of CD4 T cells in BCG induced immunity, we sought to characterise the generation of memory C...

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Hauptverfasser: Kaveh, Daryan A., Bachy, Véronique S., Hewinson, R. Glyn, Hogarth, Philip J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123368/
https://ncbi.nlm.nih.gov/pubmed/21720558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021566
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