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New Structural and Functional Contexts of the Dx[DN]xDG Linear Motif: Insights into Evolution of Calcium-Binding Proteins

Binding of calcium ions (Ca(2+)) to proteins can have profound effects on their structure and function. Common roles of calcium binding include structure stabilization and regulation of activity. It is known that diverse families – EF-hands being one of at least twelve – use a Dx[DN]xDG linear motif...

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Detalhes bibliográficos
Main Authors: Rigden, Daniel J., Woodhead, Duncan D., Wong, Prudence W. H., Galperin, Michael Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123361/
https://ncbi.nlm.nih.gov/pubmed/21720552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021507
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