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A Novel Missense Mutation in the Connexin30 Causes Nonsyndromic Hearing Loss

Dysfunctional gap junctions caused by GJB2 (CX26) and GJB6 (CX30) mutations are implicated in nearly half of nonsyndromic hearing loss cases. A recent study identified a heterozygous mutation, c.119C>T (p.A40V), in the GJB6 gene of patients with nonsyndromic hearing loss. However, the functional...

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Hlavní autoři: Wang, Wen-Hung, Liu, Yu-Fan, Su, Ching-Chyuan, Su, Mao-Chang, Li, Shuan-Yow, Yang, Jiann-Jou
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123352/
https://ncbi.nlm.nih.gov/pubmed/21731760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021473
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