Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells

BACKGROUND: The Shc isoforms is known to mediate immune responses and has been indicated as a negative regulator of autoimmunity and lymphocyte activation. We aimed to evaluate the immune-regulatory role of Shc in rat bone marrow-derived DCs in the maturation process triggered by LPS. RESULTS: We fo...

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Detalhes bibliográficos
Main Authors: Chen, Kuang-Den, Hsu, Li-Wen, Goto, Shigeru, Yeh, Chin-Wei, Nakano, Toshiaki, Lai, Chia-Yun, Chang, Yen-Chen, Hou, Chiung-Hui, Wang, Chih-Chi, Cheng, Yu-Fan, Chiu, King-Wah, Lin, Chih-Che, Chen, Chao-Long
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123310/
https://ncbi.nlm.nih.gov/pubmed/21612602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-32
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