Concurrent Detection of Circulating Minor Histocompatibility Antigen-Specific CD8(+) T Cells in SCT Recipients by Combinatorial Encoding MHC Multimers

Allogeneic stem cell transplantation (SCT) is a potentially curative treatment for patients with hematologic malignancies. Its therapeutic effect is largely dependent on recognition of minor histocompatibility antigens (MiHA) by donor-derived CD8(+) T cells. Therefore, monitoring of multiple MiHA-sp...

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Detalhes bibliográficos
Main Authors: Broen, Kelly, Greupink-Draaisma, Annelies, Woestenenk, Rob, Schaap, Nicolaas, Brickner, Anthony G., Dolstra, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123304/
https://ncbi.nlm.nih.gov/pubmed/21731686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021266
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