In vitro-generated interspecific recombinants between bovine herpesviruses 1 and 5 show attenuated replication characteristics and establish latency in the natural host

BACKGROUND: Interspecific recombinant viruses R1ΔgC and R2ΔgI were isolated after in vitro co-infection with BoHV-1 and BoHV-5, two closely related alphaherpesviruses that infect cattle. The genetic characterization of R1ΔgC and R2ΔgI showed that they are composed of different sections of the parent...

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Hauptverfasser: Del Medico Zajac, Maria P, Romera, Sonia A, Ladelfa, María F, Kotsias, Fiorella, Delgado, Fernando, Thiry, Julien, Meurens, François, Keil, Günther, Thiry, Etienne, Muylkens, Benoît
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123189/
https://ncbi.nlm.nih.gov/pubmed/21592326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-7-19
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