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A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains

BACKGROUND: Modeling of transmembrane domains (TMDs) requires correct prediction of interfacial residues for in-silico modeling and membrane insertion studies. This implies the defining of a target sequence long enough to contain interfacial residues. However, too long sequences induce artifactual p...

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Main Authors: Charlois, Yan, Lins, Laurence, Brasseur, Robert
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123172/
https://ncbi.nlm.nih.gov/pubmed/21605471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-26
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