Deimination of Human Filaggrin-2 Promotes Its Proteolysis by Calpain 1

Filaggrin-2 (FLG2), a member of the S100-fused type protein family, shares numerous features with filaggrin (FLG), a key protein implicated in the epidermal barrier functions. Both display a related structural organization, an identical pattern of expression and localization in human epidermis, and...

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Main Authors: Hsu, Chiung-Yueh, Henry, Julie, Raymond, Anne-Aurélie, Méchin, Marie-Claire, Pendaries, Valérie, Nassar, Dany, Hansmann, Britta, Balica, Stéfana, Burlet-Schiltz, Odile, Schmitt, Anne-Marie, Takahara, Hidenari, Paul, Carle, Serre, Guy, Simon, Michel
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123089/
https://ncbi.nlm.nih.gov/pubmed/21531719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197400
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