Iron Regulatory Protein 1 Outcompetes Iron Regulatory Protein 2 in Regulating Cellular Iron Homeostasis in Response to Nitric Oxide

In mammals, iron regulatory proteins (IRPs) 1 and 2 posttranscriptionally regulate expression of genes involved in iron metabolism, including transferrin receptor 1, the ferritin (Ft) H and L subunits, and ferroportin by binding mRNA motifs called iron responsive elements (IREs). IRP1 is a bifunctio...

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Main Authors: Styś, Agnieszka, Galy, Bruno, Starzyński, Rafal R., Smuda, Ewa, Drapier, Jean-Claude, Lipiński, Pawel, Bouton, Cécile
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123052/
https://ncbi.nlm.nih.gov/pubmed/21566147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231902
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