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Disruption of the Murine Protein Kinase Cβ Gene Promotes Gallstone Formation and Alters Biliary Lipid and Hepatic Cholesterol Metabolism

The protein kinase C (PKC) family of Ca(2+) and/or lipid-activated serine-threonine protein kinases is implicated in the pathogenesis of obesity and insulin resistance. We recently reported that protein kinase Cβ (PKCβ), a calcium-, diacylglycerol-, and phospholipid-dependent kinase, is critical for...

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Autors principals: Huang, Wei, Bansode, Rishipal R., Xie, Yan, Rowland, Leslie, Mehta, Madhu, Davidson, Nicholas O., Mehta, Kamal D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123047/
https://ncbi.nlm.nih.gov/pubmed/21550971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.250282
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