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Priming CD8(+) T cells with dendritic cells matured using TLR4 and TLR7/8 ligands together enhances generation of CD8(+) T cells retaining CD28
TLRs expressed on dendritic cells (DCs) differentially activate DCs when activated alone or in combination, inducing distinct cytokines and costimulatory molecules that influence T-cell responses. Defining the requirements of DCs to program T cells during priming to become memory rather than effecto...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123022/ https://ncbi.nlm.nih.gov/pubmed/21493800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-317966 |
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