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TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs

In addition to the well-recognized role in extracellular matrix remodeling, the tissue inhibitor of metalloproteinases-1 (TIMP-1) has been suggested to be involved in the regulation of numerous biologic functions, including cell proliferation and survival. We therefore hypothesized that TIMP-1 might...

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Autori principali: Rossi, Lara, Ergen, Aysegul V., Goodell, Margaret A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123018/
https://ncbi.nlm.nih.gov/pubmed/21521782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-248955
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