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Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP.
The glucose/insulin response element of the L-pyruvate kinase gene is a perfect palindrome located from nt -168 to -144 with respect to the cap site. This element (L4) is partially homologous to MLTF binding sites. Its full efficiency requires cooperation with a contiguous binding site for HNF4, ter...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1992
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312300/ https://ncbi.nlm.nih.gov/pubmed/1315961 |
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