Pathogen-Specific DNA Enrichment Does Not Increase Sensitivity of PCR for Diagnosis of Invasive Aspergillosis in Neutropenic Patients

PCR assays designed for the diagnosis of invasive aspergillosis (IA) in high-risk patients have to detect minute amounts of target DNA to reach sufficient analytical sensitivity to be of clinical use. This prospective study assessed the use of a novel strategy for selective pathogen DNA enrichment f...

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Hlavní autoři: Springer, Jan, Loeffler, Juergen, Heinz, Werner, Schloßnagel, Hannes, Lehmann, Marc, Morton, Oliver, Rogers, Thomas R., Schmitt, Corinna, Frosch, Matthias, Einsele, Hermann, Kurzai, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Mycology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122848/
https://ncbi.nlm.nih.gov/pubmed/21191054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01679-10
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